Artigos Publicados
2025
Fagundes TP, Caetano GA, Ribas VT, Calderaro DC, Castro UB. Chitosan conduits for peripheral nerve repair: a systematic review of animal studies. Braz J Biol. 2024;84:e280569. Available from: https://doi.org/10.1590/1519-6984.280569
2024
Almeida RA, Ferreira CG, Matos VUS, Nogueira JM, Braga MP, Caldi Gomes L, Jorge EC, Soriani FM, Michel U, Ribas VT. AAV-Mediated Expression of miR-17 Enhances Neurite and Axon Regeneration In Vitro. Int J Mol Sci. 2024 Aug 21;25(16):9057. doi: 10.3390/ijms25169057.
De Lima S, Mietto BS, Ribas VT, Ribeiro-Resende VT, Oliveira ALR, Park KK. Editorial: Promoting nervous system regeneration by treatments targeting neuron-glia interactions. Front Cell Neurosci. 2024 Jan 11;17:1355469. doi: 10.3389/fncel.2023.1355469.
2023
Vasconcelos CFM, Ribas VT, Petrs-Silva H. Shared Molecular Pathways in Glaucoma and Other Neurodegenerative Diseases: Insights from RNA-Seq Analysis and miRNA Regulation for Promising Therapeutic Avenues. Cells. 2023 Aug 28;12(17):2155. doi: 10.3390/cells12172155.
2022
Dias MS, Luo X, Ribas VT, Petrs-Silva H, Koch JC. The Role of Axonal Transport in Glaucoma. Int J Mol Sci. 2022 Apr 1;23(7):3935. doi: 10.3390/ijms23073935.
Lani-Louzada R, Marra C, Dias MS, de Araújo VG, Abreu CA, Ribas VT, Adesse D, Allodi S, Chiodo V, Hauswirth W, Petrs-Silva H, Linden R. Neuroprotective Gene Therapy by Overexpression of the Transcription Factor MAX in Rat Models of Glaucomatous Neurodegeneration. Invest Ophthalmol Vis Sci. 2022 Feb 1;63(2):5. doi: 10.1167/iovs.63.2.5.
2021
Ribas VT, Vahsen BF, Tatenhorst L, Estrada V, Dambeck V, Almeida RA, Bähr M, Michel U, Koch JC, Müller HW, Lingor P. AAV-mediated inhibition of ULK1 promotes axonal regeneration in the central nervous system in vitro and in vivo. Cell Death Dis. 2021 Feb 26;12(2):213. doi: 10.1038/s41419-021-03503-3.
Lani-Louzada R, Dias MS, Linden R, Ribas VT, Petrs-Silva H. Gene Therapy Strategies for Glaucomatous Neurodegeneration. Curr Gene Ther. 2021;21(5):362-381. doi: 10.2174/1566523221666210126152000.
2020
Vahsen BF, Ribas VT, Sundermeyer J, Boecker A, Dambeck V, Lenz C, Shomroni O, Caldi Gomes L, Tatenhorst L, Barski E, Roser AE, Michel U, Urlaub H, Salinas G, Bähr M, Koch JC, Lingor P. Inhibition of the autophagic protein ULK1 attenuates axonal degeneration in vitro and in vivo, enhances translation, and modulates splicing. Cell Death Differ. 2020 Oct;27(10):2810-2827. doi: 10.1038/s41418-020-0543-y.
Balke D, Tatenhorst L, Dambeck V, Ribas VT, Vahsen BF, Michel U, Bähr M, Lingor P. AAV-Mediated Expression of Dominant-Negative ULK1 Increases Neuronal Survival and Enhances Motor Performance in the MPTP Mouse Model of Parkinson’s Disease. Mol Neurobiol. 2020 Feb;57(2):685-697. doi: 10.1007/s12035-019-01744-0.
2017
Ribas VT, Costa MR. Gene Manipulation Strategies to Identify Molecular Regulators of Axon Regeneration in the Central Nervous System. Front Cell Neurosci. 2017 Aug 7;11:231. doi: 10.3389/fncel.2017.00231.
Ribas VT, Koch JC, Michel U, Bähr M, Lingor P. Attenuation of Axonal Degeneration by Calcium Channel Inhibitors Improves Retinal Ganglion Cell Survival and Regeneration After Optic Nerve Crush. Mol Neurobiol. 2017 Jan;54(1):72-86. doi: 10.1007/s12035-015-9676-2.
2016
Ribas VT, Lingor P. Calcium channel inhibition-mediated axonal stabilization improves axonal regeneration after optic nerve crush. Neural Regen Res. 2016 Aug;11(8):1245-6. doi: 10.4103/1673-5374.189184.
2015
Ribas VT, Lingor P. Autophagy in degenerating axons following spinal cord injury: evidence for autophagosome biogenesis in retraction bulbs. Neural Regen Res. 2015 Feb;10(2):198-200. doi: 10.4103/1673-5374.152367.
Challagundla M, Koch JC, Ribas VT, Michel U, Kügler S, Ostendorf T, Bradke F, Müller HW, Bähr M, Lingor P. AAV-mediated expression of BAG1 and ROCK2-shRNA promote neuronal survival and axonal sprouting in a rat model of rubrospinal tract injury. J Neurochem. 2015 Jul;134(2):261-75. doi: 10.1111/jnc.13102.
Saal KA, Koch JC, Tatenhorst L, Szegő EM, Ribas VT, Michel U, Bähr M, Tönges L, Lingor P. AAV.shRNA-mediated downregulation of ROCK2 attenuates degeneration of dopaminergic neurons in toxin-induced models of Parkinson’s disease in vitro and in vivo. Neurobiol Dis. 2015 Jan;73:150-62. doi: 10.1016/j.nbd.2014.09.013.
Ribas VT, Schnepf B, Challagundla M, Koch JC, Bähr M, Lingor P. Early and sustained activation of autophagy in degenerating axons after spinal cord injury. Brain Pathol. 2015 Mar;25(2):157-70. doi: 10.1111/bpa.12170.
2012
Ribas VT, Gonçalves BS, Linden R, Chiarini LB. Activation of c-Jun N-terminal kinase (JNK) during mitosis in retinal progenitor cells. PLoS One. 2012;7(4):e34483. doi: 10.1371/journal.pone.0034483.
2011
Ribas VT, Arruda-Carvalho M, Linden R, Chiarini LB. Early c-Jun N-terminal kinase-dependent phosphorylation of activating transcription factor-2 is associated with degeneration of retinal ganglion cells. Neuroscience. 2011 Apr 28;180:64-74. doi: 10.1016/j.neuroscience.2011.01.059.
2009
Martini SV, Fagundes SS, Schmidt AC, Avila M, Ornellas DS, Ribas VT, Petrs-Silva H, Linden R, Faffe DS, Guggino SE, Rocco PR, Zin WA, Morales MM. Does the use of recombinant AAV5 in pulmonary gene therapy lead to lung damage? Respir Physiol Neurobiol. 2009 Sep 30;168(3):203-9. doi: 10.1016/j.resp.2009.06.016.